genome

Medical Ethics - Genetics
2:17 pm
Tue March 4, 2014

Whole Genome Sequencing Is Here To Stay. What Does That Mean For Genetic Privacy?

Adenine, thymine, cytosine and guanine (abbreviated ATCG) are the four nucleotide bases that make up DNA.
Credit Jane Ades, NHGRI

Originally published on Wednesday, February 26, 2014. Updated to include audio from St. Louis on the Air.

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St. Louis on the Air
6:45 pm
Mon June 10, 2013

Wash U Has Four Of The World’s Top Researchers

Professor Richard K. Wilson, Director of the Genomics Institute at Washington University in St. Louis
(Courtesy: Washington University in St. Louis)

Four of the top twenty-one influential researchers in the world live in the St. Louis area.

The researchers are from Washington University in St. Louis and all are in the field of genomics.  The findings come from Thomson Reuters ScienceWatch, an open web resource for science metrics and analysis.

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Cancer Research
12:02 pm
Wed May 1, 2013

Wash U Maps Genomes Of Two Major Cancers, Could Impact Treatment

Lines in this circos plot connect major genes involved in acute myeloid leukemia with patients whose leukemia cells have mutations in those genes.
Credit Benjamin Raphael, Brown University

In separate studies both published today, researchers at Washington University mapped the genomes of two types of cancer: endometrial cancer, and acute myeloid leukemia.

Both studies are part of The Cancer Genome Atlas project, an effort funded by the National Institutes of Health to study the genetic basis of 20 major human cancers.

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Human Genetics
5:55 pm
Wed October 31, 2012

International Consortium Sequences 1000 Human Genomes

Adenine, thymine, cytosine and guanine (abbreviated ATCG) are the four nucleotide bases that make up DNA.
Jane Ades, NHGRI

An international consortium of researchers has sequenced the genomes of more than 1000 people, creating the largest catalog yet of human genetic variation.

Richard Wilson directs the Washington University Genome Institute, one of four major research institutions involved in the 1000 Genomes Project.

He says researchers identified rare genetic variants that may eventually explain why some people are more susceptible to certain diseases like cancer or Alzheimer’s.

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Human Genome - Privacy
5:50 pm
Thu October 11, 2012

Federal Commission Calls For Stronger Protections For Human Genome Data

Adenine, thymine, cytosine and guanine (abbreviated ATCG) are the four nucleotide bases that make up DNA. The sequence of each person’s genetic code is unique.
Jane Ades, NHGRI

A federal panel is calling for stronger privacy protections for human genetic data.

In a report out today, the Presidential Commission for the Study of Bioethical Issues said “whole genome sequencing” — which provides a unique blueprint of each person’s DNA —  holds great promise for advancing medical research and clinical care.

But the Commission said genetic data can also be misused and need to be adequately protected.

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12:37 pm
Wed September 5, 2012

'Google Maps' for human genome unveiled - with a St. Louis connection

There's a local connection to this development - The Genome Institute at Washington University School of Medicine says they "played an important role in this project by generating genome sequence data." Learn more via the link.
Scientists unveiled the results of a massive international project Wednesday that they say debunks the notion that most of our genetic code is made up of so-called junk DNA. The ENCODE project, which involved hundreds of researchers in dozens of labs, also produced what some scientists are saying is like Google Maps for the human genome.
Genetics
12:33 pm
Wed January 26, 2011

Researchers sequence genome of endangered orangutans

In the Malay language, oran-utan means "man of the forest." (Perry van Duijnhoven/Carel van Schaik)

An international team of researchers has sequenced the genomes of two species of orangutan.

Lead researcher Devin Locke of the Genome Center at Washington University said a primary motivation for studying the genes of orangutans is their close evolutionary relationship to humans.

“The lessons you learn from studying these species can be applied to understanding of our own evolution and the evolution of the human population as well,” Locke said.

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