Washington University

Washington University School of Medicine

Washington University School of Medicine has received a $50 million federal grant aimed at turning research findings into improvements in human health.

The grant is the renewal of an award from the National Institutes of Health. It will support Wash U's Institute of Clinical and Translational Sciences (ICTS), one of 60 such centers in the U.S.

Jane Ades, NHGRI

An international consortium of researchers has sequenced the genomes of more than 1000 people, creating the largest catalog yet of human genetic variation.

Richard Wilson directs the Washington University Genome Institute, one of four major research institutions involved in the 1000 Genomes Project.

He says researchers identified rare genetic variants that may eventually explain why some people are more susceptible to certain diseases like cancer or Alzheimer’s.

Robert Boston/Washington University

A popular supplement made from a component of red wine may not be beneficial after all – at least if you’re healthy to start with.

That’s according to a new study out of Washington University – the first to test the potential benefits of resveratrol in healthy people.

(via Flickr/kennedy22)

Clinical depression is called the world’s number one mental disorder and ranks only behind heart disease as the country’s most disabling condition.  It is also dangerous because it can all too often lead to suicide.  Andrew and Barbara Taylor and the Crawford Taylor Foundation have committed $20 million to Washington University to fund research on mental illness, with a sharp focus on depression.

(Courtesy Ian Nichols)

For more than a decade, Washington University anthropologist Crickette Sanz and Lincoln Park Zoo research conservationist David Morgan have lived and worked in a remote stretch of forest in Africa’s Congo Basin, studying chimpanzees and gorillas.

Together with local Congolese, they founded the Goualougo Triangle Ape Project, whose mission is to study and protect great apes and their habitat.

Sanz and Morgan are giving a talk about their work tonight at the St. Louis Zoo — they spoke with St. Louis Public Radio's Véronique LaCapra.

Tammie Benzinger, MD, PhD, Tyler Blazey/Washington University

Washington University will soon lead a clinical trial aimed at preventing people with Alzheimer’s disease from developing dementia.

The international trial will involve 160 patients in the U.S., Europe, and Australia who have a very rare, inherited form of Alzheimer’s, which typically causes dementia before age 50.

Washington University neurologist and study lead Dr. Randall Bateman says this is one of the first clinical trials to try to treat Alzheimer’s patients before they have any symptoms.

U.S. Department of Health & Human Services

Washington University is hosting a conference tomorrow afternoon on public health challenges in the 21st century.

Melissa Jonson-Reid directs Wash U's Brown Center for Violence and Injury Prevention.

She says one challenge the conference will take on is the problem of violence in St. Louis, and the role local public health professionals can play in addressing it.

Washington University School of Medicine

Washington University School of Medicine has received a $20 million donation to establish a new center for psychiatric research.

The Taylor Family Institute for Innovative Psychiatric Research will focus on developing new and more effective therapies for psychiatric disorders. Researchers will start by studying neurosteroids, chemicals in the brain that help regulate thinking and emotion. Changes in levels of neurosteroids can be linked to mood disorders, chronic pain, epilepsy, or Alzheimer’s disease.

US National Institute on Aging, Alzheimer's Disease Education and Referral Center

Finding effective treatments and a cure for Alzheimer’s disease is elusive.  While most of what we hear about the disease is depressing, we may be on the threshold of some exciting discoveries concerning prevention.  Washington University’s School of Medicine is in the middle of this new research and this hour, host Don Marsh is joined by Dr. John Morris, Director of Washington University’s Alzheimer’s Research Center, to talk about clinical trials aimed at preventing Alzheimer’s disease.

There's a local connection to this development - The Genome Institute at Washington University School of Medicine says they "played an important role in this project by generating genome sequence data." Learn more via the link.

(via Wikimedia Commons/Leonardo da Vinci, Galleria dell' Accademia, Venice (1485-90)

People are sometimes used as test subjects in scientific research – from clinical trials, to studies on the toxicity of pesticides.

The federal government is currently revising the regulation designed to protect human research subjects from harm.

Washington University law professor Rebecca Dresser wrote an article published in the journal Science, talking about some changes she’d like to see made. She spoke with St. Louis Public Radio's Véronique LaCapra.

(Image courtesy of the NASA Jet Propulsion Laboratory)

Not long after midnight central time tonight, the rover known as Curiosity will land on Mars.

It will take the rover seven minutes to get from the Mars atmosphere to the planet's surface. But because it takes about twice that long for signals to travel from Mars to Earth, scientists won't know anything about the landing until after it's already over.

Scott Supplesa

Pediatric leukemia is a cancer of the blood and bone marrow. There are about 3,000 new cases in the United States every year, typically in children between the ages of four and six.

With treatment, about three-quarters of affected children are able to beat the disease.

But for those with what’s known as “high risk” leukemia, the odds of survival are much worse.

Washington University pediatric oncologist Dr. Todd Druley has been trying to use genetics to understand why some leukemia is so hard to treat. He spoke with St. Louis Public Radio's Véronique LaCapra.

The associate director of Washington University in St. Louis' Genome Institute, George Weinstock, was one of this project's lead researchers. He says we have about ten times more microbial cells in our body than we have human cells. He told our reporter Véronique LaCapra today: “...there’s probably a hundred times or more microbial genes in our body than there are genes in our human genome,” Weinstock said. “So the microbes, they’re not just a small little part of us, they’re really a very, very large, perhaps almost dominant part of our body.”

U.S. Department of Agriculture

Researchers have completed the first comprehensive census of the human “microbiome” — the trillions of bacteria, viruses, and other microorganisms that live in and on our bodies.

The associate director of Washington University’s Genome Institute, George Weinstock, was one of the project’s lead researchers. He says we have about ten times more microbial cells in our body than we have human cells.

(via Flickr/Indofunk Satish)

Finding from Washington University could hold key to more targeted breast cancer treatments

Researchers at Washington University have uncovered a genetic mutation that explains why some women don't respond to a common form of breast cancer treatment.

Before surgery, most women with breast cancer receive aromatase inhibitors, which reduce the production of estrogen to shrink the size of tumors. But it doesn't always work.

(via Flickr/IndofunkSatish)

Ameren, Westinghouse to give more details on nuclear partnership

Missouri regulators will learn more today about a proposal to build small nuclear reactors at Ameren Missouri's Callaway nuclear power plant.

WashU study says folic acid may fight childhood cancer

May 21, 2012

A new study by Washington University indicates that folic acid may be responsible for reductions in certain kinds of childhood cancer.

Kimberly Johnson is an Assistant Professor of Public Health at Washington University, she says  folic acid has been a supplement in enriched grains since 1998.

“The study says that there is a correlation between fortification of the food supply,  with folic acid and a reduction in the incidence of some types of childhood cancer,” says Johnson.

(via Flickr/IndofunkSatish)

Federal court sides with Quinn in pay dispute

A federal appeals court has sided with Illinois governor Pat Quinn over canceled pay raises due to thousands of union workers.

(via Wikimedia Commons)

Today is the Cardinals' home opener against the Chicago Cubs.

For St. Louis Public Radio’s Véronique LaCapra, baseball season means it’s time to talk about the science behind America’s national pastime.

And Washington University aerospace engineer David Peters was happy to join in.

(National Cancer Institute)

More than half of cancer cases in the United States could be prevented.

That’s according to a new article published this week in the journal Science Translational Medicine by researchers at the Siteman Cancer Center and Washington University.

St. Louis Public Radio's Véronique LaCapra spoke with lead author Dr. Graham Colditz about what we know about cancer — and why more isn’t being done to prevent it.

(Image courtesy National Institute on Aging)

A new marker for Alzheimer's disease can be used to predict how quickly a patient will develop memory loss and other symptoms of dementia.

Researchers at Washington University measured levels of a marker called visinin-like protein 1 in in the spinal fluid of 60 patients in the early stages of Alzheimer's then tracked their symptoms for three years.

Neurologist Dr. Rawan Tarawneh, now at the University of Jordan, led the study.

(via Flickr/pasa47)

The already booming University City Loop is about to get a big infusion of money - an $80 million project by nearby Washington University.

The St. Louis Post-Dispatch reports the plan calls for development of stores in a four- to six-story building, along with apartments for about 550 students. Design work will begin soon and construction could start as early as next January.

The housing units could be occupied starting in August 2014.

(Photo: Jason Wolff/UNC)

New research shows that differences in the brain development of autistic children are already visible in infants as young as 6 months old.

Researchers at four study sites nationwide used a type of MRI scan to look at brain development in the younger siblings of autistic children, who are known to be at higher risk for autism themselves.

Ninety-two children were scanned at 6, 12, and 24 months of age, while the children were sleeping.

(Image courtesy of NIAID)

There is growing evidence that taking antibiotics does not help cure most sinus infections.

A new study out of Washington University compared sinus patients who were given the antibiotic amoxicillin to others who were given a placebo.

(Joe Angeles/WUSTL)

U.S. Senator Claire McCaskill was in St. Louis Monday as part of her state-wide energy tour.

The Democratic senator participated in a roundtable discussion at Washington University about the nation's energy future. At the table were some of Missouri's energy industry leaders, along with university administrators and researchers.

McCaskill says their feedback reinforced for her the need to keep all energy options on the table.

(National Cancer Institute)

There's more evidence that most men don’t need an annual prostate cancer screening.

Washington University chief urologist Dr. Gerald Andriole has been leading a clinical trial involving more than 75,000 men over the age of 55.

The study has tracked the men for over a decade, to see whether getting an annual prostate-specific antigen, or PSA test, makes someone less likely to die from prostate cancer.

(Jon Wingo/DJM Ecological Services)

Researchers are conducting controlled burns this week at Washington University’s Tyson Research Center southwest of St. Louis.

The burns are part of a project to study how to restore Ozark glades – rocky forest clearings with native species that resemble those of the desert southwest.

Washington University ecologist and project lead Tiffany Knight says fire is a natural part of glade ecosystems.

(via Flickr/MoneyBlogNewz)

Smoking bans were implemented in several areas in St. Louis in 2011, including in the city and county.

Sarah Shelton, a data analyst with the Center for Tobacco Policy Research at Washington University in St. Louis, told St. Louis Public Radio’s Julie Bierach as part of our series “A Good Year” that, overall, it’s been a good year for non-smokers.

(provided by Carla Alexander)

On the corner of Garrison and Sheridan in St. Louis stands a vacant building that for decades housed a thriving African American business. Its owner is remembered as an entrepreneur and informal activist during the civil rights movement. But now, the building is crumbling.