The day Sha Fields was diagnosed with breast cancer in 2007, her fiancé came along to offer moral support, and he has been by her side since then. She says she used to wonder how to repay his years of unconditional support. The chance came last year, when the husband, Cliff, was diagnosed with prostate cancer. The Siteman Center for Advanced Medicine at Washington University had no data on how unusual it is for a husband and wife to have cancer, but Sha says she is hearing that the experience is becoming more common.
When Sally O'Neill's doctor told her she had an early form of cancer in one of her breasts, she didn't agonize about what she wanted to.
The 42-year-old mother of two young girls wanted a double mastectomy.
"I decided at that moment that I wanted them both taken off," says O'Neill, who lives in a suburb of Boston. "There wasn't a real lot of thought process to it. I always thought, 'If this happens to me, this is what I'm going to do.' Because I'm not taking any chances. I want the best possible outcome. I don't want to do a wait-and-see."
The top image shows untreated breast cancer cells with HER2 mutations. The bottom image shows how much these cells shrink after treatment with neratinib, an anti-HER2 drug currently in clinical trials.
Credit (via Washington University in St. Louis/Shyam Kavuri, Ph. D.)
The findings of new breast cancer research from Washington University could result in effective treatment for 4,000 additional patients in the United States each year. Scientists made the discovery after analyzing DNA sequencing data from 1,500 patients.
The research appears in the latest edition of Cancer Discovery.
Researchers at Washington University used new technology to unravel the entire genetic helix for a subset of breast cancer, called basal-like, and found that it is more like ovarian cancer than other types of breast cancer.
The study’s co-Leader, Mathew Ellis, said that means techniques used to tackle ovarian cancer could be more effective than traditional methods for basal-like breast cancer.
“The more we understand about an individual breast cancer the more we can actually treat the patient accurately,” Ellis said. “I like to call this genome forward medicine.”
The $6.6 million robbery of ATM Solutions in St. Louis in 2010 is believed to be the largest heist ever in St. Louis. It turns out the robbers themselves were victimized, too - at least $1.3 million was re-stolen.